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KMID : 0377819900100111304
Diagnosis and Treatment
1990 Volume.10 No. 11 p.1304 ~ p.1309
PRIMARY DEGENRATIVE DEMENTIA OF THE ALZHEIMER TYPE
ÀÓŽÄ/Lim, Tae Shik
±è±¤¼ö/À¯Å¿­/Kim, Kwang Soo/Lew, Tae Yul
Abstract
Dementia, loss of intellectual function, is defined as generalized impairment of cognitive function that is usually progressive but not associated with a depressed, level of consciousness, and is common -in western society, and it. is becoming more common as the age of the population gradually increases. Primary Degenerative Dementia(PDD) .of. the Alzheimer type is by far the single most common cause of dementia usually. presenting in patients over 50 years of age. There is early and severe involvement of memory and usually lost insight. It gradually affects all aspects of intellectual function. The disease, and the dementia it causes, are insidious and patients often present very late. The slowly progressive disorder ` of unknown cause that cannot be diagnosed with certainty on clinical grounds, it is characterized by typical histopathologic features (neurofibrillary tangles, senile neuritic plaques, and granulovacular degeneration).
Although a distribution was formerly made between presenile and senile forms, these conditions appears to be identical clinically and pathologically. No treatment is available at present, and care in a nursing facility may be necessary in advanced stage of the disorder. Not only psychiatrists but also physicians and general practitioners should be aware of the differential diagnosis of this disorder, and exclude out other treatable causes of dementia from the PDD of Alzheimer type.
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